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PrEP: ONCE-A-DAY HELPS PREVENT HIV!
PrEP offers an effective way for individuals to prevent HIV infection from taking hold and spreading in the body. Anyone who is sexually active and HIV-negative can benefit from PrEP.

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ABOUT PrEP
What is PrEP HIV?
PrEP (pre-exposure prophylaxis) is medicine that reduces your chances of getting HIV from sex or injection drug use. When taken as prescribed, PrEP is highly effective for preventing HIV.
Are there different types of PrEP?
PrEP can be pills or shots.
There are two pills approved for use as PrEP: Truvada® and Descovy®.
Truvada® is for people at risk through sex or injection drug use.
Descovy® is for people at risk through sex. Descovy is not for people assigned female at birth who are at risk for HIV through receptive vaginal sex.
Apretude is the only shot approved for use as PrEP. Apretude is for people at risk through sex who weigh at least 77 pounds (35 kg).
Can I switch from pills to shots?
Talk to your health care provider about switching from PrEP pills to shots. PrEP shots may be right for you if you do not have HIV and have no known allergy to the medicines in the shot.
If you decide to switch from PrEP pills to shots, you’ll need to visit your health care provider regularly to receive your shot. You’ll also need to be tested for HIV prior to each PrEP shot.
Is PrEP safe?
PrEP is safe, but some people experience side effects like diarrhea, nausea, headache, fatigue, and stomach pain. These side effects usually go away over time.
Tell your healthcare provider about any side effects that are severe or do not go away.
PrEP (pre-exposure prophylaxis prep for HIV prevention) is medicine that reduces your chances of getting HIV from sex or injection drug use. When taken as prescribed, PrEP is highly effective for preventing HIV.
Are there different types of PrEP?
There are two pills approved for use as PrEP: Truvada® and Descovy®.
- Truvada®: is for people at risk through sex or injection drug use.
- Descovy®: is for people at risk through sex. Descovy is not for people assigned female at birth who are at risk for HIV through receptive vaginal sex.
- Apretude: is the only shot approved for use as PrEP. Apretude is for people at risk through sex who weigh at least 77 pounds (35 kg).
Can I switch from pills to shots?
If you decide to switch from PrEP pills to shots, you’ll need to visit your health care provider regularly to receive your shot. You’ll also need to be tested for HIV prior to each PrEP shot.
Is PrEP safe?
HIV PrEP is safe, but some people experience side effects like diarrhea, nausea, headache, fatigue, and stomach pain. These side effects usually go away over time.
Tell your health care provider about any side effects that are severe or do not go away.
PrEP EFFECTIVENESS
How effective is PrEP?
PrEP is highly effective for preventing HIV.
- PrEP HIV reduces the risk of getting HIV from sex by about 99% when taken as prescribed.
- Although there is less information about how effective PrEP pills are among people who inject drugs, we know that PrEP pills reduce the risk of getting HIV by at least 74% when taken as prescribed. Currently, PrEP shots are not recommended for people who inject drugs.
- PrEP is less effective when not taken as prescribed.
How long does PrEP take to work?
- For receptive anal sex (bottoming), PrEP pills reach maximum protection from HIV at about 7 days of daily use.
- For receptive vaginal sex and injection drug use, PrEP pills reach maximum protection at about 21 days of daily use.
- No data are available for PrEP pill effectiveness for insertive anal sex (topping) or insertive vaginal sex.
- We don’t know how long it takes for PrEP shots to reach maximum protection during sex.
PAYING FOR PrEP
How can I pay for PrEP?
Most insurance plans and state Medicaid programs cover PrEP. Under the Affordable Care Act, PrEP must be free under almost all health insurance plans. That means you can’t be charged for your PrEP medication or the clinic visits and lab tests you need to maintain your prescription.
If you don’t have insurance or Medicaid coverage, there are other programs that provide PrEP HIV for free or at a reduced cost.
DECIDING TO TAKE PrEP
Is PrEP right for me?

- have a sexual partner with HIV (especially if the partner has an unknown or detectable viral load),
- have not consistently used a condom, or
- have been diagnosed with a sexually transmitted disease in the past 6 months.

You inject drugs and you
- have an injection partner with HIV, or
- share needles, syringes, or other drug injection equipment (for example, cookers).

You have been prescribed PEP (post-exposure prophylaxis) and you
- report continued risk behavior, or
- have used multiple courses of PEP.
You may choose to take PrEP, even if the behaviors listed above don’t apply to you. Talk to your health care provider.
Can I take PrEP during pregnancy or while breastfeeding?
Can adolescents take PrEP?
CONTINUING PrEP
Why do I need to take PrEP as prescribed?
- You must take PrEP as prescribed for it to work.
- If you do not take PrEP as prescribed, there may not be enough medicine in your bloodstream to block the virus.
- The right amount of medicine in your bloodstream can stop HIV from taking hold and spreading in your body.
Can I take PrEP while on birth control?
There are no known interactions between PrEP and hormone-based birth control methods, e.g., the pill, patch, ring, shot, implant, or IUD. It is safe to use both at the same time.
Will PrEP interfere with my hormone therapy?
There are no known drug conflicts between PrEP and hormone therapy, and there is no reason why the drugs cannot be taken at the same time.
Can I stop using condoms if I take PrEP?
- PrEP provides protection from HIV but does not protect against other sexually transmitted diseases (STDs) or prevent pregnancy.
- Condoms can help prevent other STDs that can be transmitted through genital fluids, such as gonorrhea and chlamydia.
- Condoms are less effective at preventing STDs that can be transmitted through sores or cuts on the skin, like human papillomavirus, genital herpes, and syphilis.

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Glades Medical Center — Doral

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